{"id":2102,"date":"2020-07-16T16:12:53","date_gmt":"2020-07-16T14:12:53","guid":{"rendered":"https:\/\/blogs.tu-braunschweig.de\/pubpharm\/?p=2102"},"modified":"2020-07-16T16:17:13","modified_gmt":"2020-07-16T14:17:13","slug":"innovative-tools-developed-by-sis-pharmacy-support-covid-19-research","status":"publish","type":"post","link":"https:\/\/blog.pubpharm.de\/index.php\/en\/2020\/07\/16\/innovative-tools-developed-by-sis-pharmacy-support-covid-19-research\/","title":{"rendered":"Innovative Tools developed by SIS Pharmacy support COVID-19 research"},"content":{"rendered":"<p>PubPharm provides up-to-date resources, e.g. preprints from the archives bioRxiv, ChemRxiv und, arXiv. Via this <a href=\"https:\/\/www.pubpharm.de\/vufind\/Search\/Results?join=AND&amp;bool0[]=AND&amp;lookfor0[]=%22novel+coronavirus%22+OR+Covid+OR+%22Sars-CoV%22+OR+%22CoV-2%22+OR+ncov&amp;type0[]=AllFields&amp;op0[]=OR&amp;limit=&amp;filter[]=publishDate:%22[2019+TO+2020]%22\" target=\"_blank\" rel=\"noopener noreferrer\">search<\/a> up-to-date publications with a focus on COVID-19\/SARS-CoV-2 can be found in PubPharm. In addition, search results can be limited using the new filter function \u201cCovid-19\/SARS-CoV-2\u201d. When <a href=\"https:\/\/www.pubpharm.de\/vufind\/Search\/Results?lookfor=%22Dexamethasone%22+&amp;submit=&amp;limit=10&amp;sort=year%2CpublishDateDaySort_date+desc\" target=\"_blank\" rel=\"noopener noreferrer\">searching for a drug substance<\/a> in PubPharm, automatically generated lists of related substances, diseases\/symptoms, and genes are displayed.<\/p>\n<p>PubPharm\u2019s AI-based facetted-search was extended to <a href=\"https:\/\/blog.pubpharm.de\/en\/2020\/06\/02\/extension-of-the-innovative-search-tool-in-pubpharm\/\" target=\"_blank\" rel=\"noopener noreferrer\">diseases and symptoms<\/a>. For example, it is now also possible to explore the learned relationships for current diseases such as <a href=\"https:\/\/www.pubpharm.de\/vufind\/Search\/Results?lookfor=covid-19\" target=\"_blank\" rel=\"noopener noreferrer\">COVID-19<\/a>. Due to the ongoing pandemic, the <a href=\"https:\/\/www.pubpharm.de\/vufind\/Search\/Results?lookfor=sars-cov-2\" target=\"_blank\" rel=\"noopener noreferrer\">links learned by the AI between SARS-COV-2<\/a> and drugs, other diseases\/symptoms, and genes are also being shown. In the area of drug-centred innovative searches, an interface based on network views was also developed.<\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-2103\" src=\"https:\/\/blog.pubpharm.de\/wp-content\/2020\/07\/2020_Netzwerke_Favipiravir-1.png\" alt=\"\" width=\"1024\" height=\"807\" srcset=\"https:\/\/blog.pubpharm.de\/wp-content\/uploads\/2020\/07\/2020_Netzwerke_Favipiravir-1.png 1024w, https:\/\/blog.pubpharm.de\/wp-content\/uploads\/2020\/07\/2020_Netzwerke_Favipiravir-1-300x236.png 300w, https:\/\/blog.pubpharm.de\/wp-content\/uploads\/2020\/07\/2020_Netzwerke_Favipiravir-1-768x605.png 768w, https:\/\/blog.pubpharm.de\/wp-content\/uploads\/2020\/07\/2020_Netzwerke_Favipiravir-1-571x450.png 571w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>Network views offer the advantage that even complex, AI-learned relationships between several drugs, diseases\/symptoms, and genes can be more easily discovered. The novel interface not only allows the exploration of pharmaceutical relationships but also provides access to the literature search capabilities of PubPharm.<\/p>\n<p>The biomedical pipeline to annotate entities like drug substances and diseases in texts was applied to the <a href=\"https:\/\/www.kaggle.com\/allen-institute-for-ai\/CORD-19-research-challenge\" target=\"_blank\" rel=\"noopener noreferrer\">CORD-19 collection<\/a>. These annotations were made available to the research community: <a href=\"https:\/\/arxiv.org\/abs\/2005.08823\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/arxiv.org\/abs\/2005.08823<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>PubPharm provides up-to-date resources, e.g. preprints from the archives bioRxiv, ChemRxiv und, arXiv. Via this search up-to-date publications with a focus on COVID-19\/SARS-CoV-2 can be found in PubPharm. In addition, search results can be limited using the new filter function \u201cCovid-19\/SARS-CoV-2\u201d. When searching for a drug substance in PubPharm, automatically generated lists of related substances, [&hellip;]<\/p>\n","protected":false},"author":179,"featured_media":1740,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[62,83,91],"tags":[],"class_list":["post-2102","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-allgemein-en","category-pubpharm-features-en","category-services-en"],"_links":{"self":[{"href":"https:\/\/blog.pubpharm.de\/index.php\/wp-json\/wp\/v2\/posts\/2102","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.pubpharm.de\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.pubpharm.de\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.pubpharm.de\/index.php\/wp-json\/wp\/v2\/users\/179"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.pubpharm.de\/index.php\/wp-json\/wp\/v2\/comments?post=2102"}],"version-history":[{"count":10,"href":"https:\/\/blog.pubpharm.de\/index.php\/wp-json\/wp\/v2\/posts\/2102\/revisions"}],"predecessor-version":[{"id":2113,"href":"https:\/\/blog.pubpharm.de\/index.php\/wp-json\/wp\/v2\/posts\/2102\/revisions\/2113"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blog.pubpharm.de\/index.php\/wp-json\/wp\/v2\/media\/1740"}],"wp:attachment":[{"href":"https:\/\/blog.pubpharm.de\/index.php\/wp-json\/wp\/v2\/media?parent=2102"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.pubpharm.de\/index.php\/wp-json\/wp\/v2\/categories?post=2102"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.pubpharm.de\/index.php\/wp-json\/wp\/v2\/tags?post=2102"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}